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Daniel Durstewitz (Computational Neuroscience, Central Institute of Mental Health, Mannheim, Germany)

"Prefrontal cortical attractor dynamics revealed by multiple single-unit recordings & multivariate analysis" / Thursday, January 21, 2010, 17:15 h
When Jan 21, 2010
from 05:00 PM to 07:00 PM
Where Lecture Hall, Hansastr. 9a
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The Bernstein Center Freiburg

Bernstein Seminar
Daniel Durstewitz
Computational Neuroscience
Central Institute of Mental Health
Mannheim, Germany

Prefrontal cortical attractor dynamics revealed by multiple single-unit recordings & multivariate analysis

Thursday, January 21, 2010

17:15 h

Lecture Hall (ground floor)
BCCN building
Hansastraße 9A
79104 Freiburg
The mammalian prefrontal cortex is involved in higher level cognitive processes like monitoring and guiding behavior. It is particularly important in novel and changing situations where new behavioral strategies have to be set up to deal with environmental challenges. Here I will present results from multiple simultaneous single-unit recordings performed from rat prefrontal cortex while the animal was situated in different working memory, decision making, and set-shifting contexts. In particular, drawing on techniques from multivariate statistics and nonlinear dynamics, we attempted to reconstruct attracting states and transitions among these states in these various behavioral contexts on a single trial basis without the help of averaging. The reconstructed neural dynamics was furthermore tightly related to and used to predict behavioral properties.
The talk is open to the public. Guests are cordially invited!


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