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Sadra Sadeh: Perturbative analysis of neural dynamics in brain networks

Department of Bioengineering, Computational Neuroscience, Imperial College London, UK [Bernstein Seminar]
When Nov 02, 2022
from 12:15 PM to 01:00 PM
Where Zoom Lecture. Meeting ID and password will be sent with e-mail invitation. You can also contact Fiona Siegfried for Meeting ID and password.
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The brain is composed of complex networks of neurons, which underlie its adaptive and versatile functionality. Recent neurotechnological developments have provided new tools for probing these networks through optogenetic perturbations, enabling investigators to go beyond observational techniques.

I present some recent theoretical and modelling work on how perturbing excitatory and inhibitory neurons can help us reveal the structure and function of cortical microcircuits. The analysis suggests that the results of perturbational interventions may not be always intuitive, given the complex network interactions, and that theory-guided perturbational analysis of brain networks is needed.


About the speaker:

Sadra Sadeh leads the Computational Lab of Neural Dynamics at Imperial College London (Department of Brain Sciences). He is the recipient of the Wellcome Trust Career Development Award (2022).
Before that, he did his postdoctoral research at University College London (Department of Neuroscience, Physiology and Pharmacology) and Imperial College London (Department of Bioengineering). He did his PhD in Computational Neuroscience at the Bernstein Center Freiburg, University of Freiburg (2015).






Supported by

Carl Zeiss FoundationNeurexNeurex | InterNeuronEU Development FundEU Interreg


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